منابع مشابه
Liposomes for Use in Gene Delivery
Liposomes have a wide array of uses that have been continuously expanded and improved upon since first being observed to self-assemble into vesicular structures. These arrangements can be found in many shapes and sizes depending on lipid composition. Liposomes are often used to deliver a molecular cargo such as DNA for therapeutic benefit. The lipids used to form such lipoplexes can be cationic...
متن کاملMannosylated liposomes for targeted gene delivery
BACKGROUND Liposomes can be modified with different ligands to control their biological properties, such as longevity, targeting ability, and intracellular penetration, in a desired fashion. The aim of this study was to modify liposomes with a novel mannosylated polyethylene glycol-phosphatidylethanolamine (M-PEG-PE) ligand to achieve active targeted gene delivery. METHODS Rat Kupffer cells w...
متن کاملCationic Liposomes in Different Structural Levels for Gene Delivery
Over the last few decades, as a promising strategy for the treatment of many refractory diseases, such as inherited diseases (Martin-Rendon & Blake, 2003) and acquired immunodeficiency syndrome (AIDS) (Fanning et al., 2003), gene therapy, the objective to allow a gene to express the protein coded in the target cells and consequently to treat disease by the protein secreted from cells transfecte...
متن کاملLiposomes as a gene delivery system.
Gene therapy is an active field that has progressed rapidly into clinical trials in a relatively short time. The key to success for any gene therapy strategy is to design a vector able to serve as a safe and efficient gene delivery vehicle. This has encouraged the development of nonviral DNA-mediated gene transfer techniques such as liposomes. Many liposome-based DNA delivery systems have been ...
متن کاملLiposomes for Drug Delivery
Bergstrand, N. 2003. Liposomes for Drug Delivery: from Physico-chemical Studies to Applications. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertation form the Faculty of Science and Technology 826. 71pp. Uppsala.
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ژورنال
عنوان ژورنال: Journal of Drug Delivery
سال: 2011
ISSN: 2090-3014,2090-3022
DOI: 10.1155/2011/326497